Liposome HandExtruder

Genizer Multi Online Liposome Extruders System can be connected with a sanitary pump or high pressure homogenizer and are temperature-controlled, from pilot testing to manufacturing production of pharmaceutical liposomes such as anti-cancer drugs. Homogenous samples can be produced quickly and easily in minutes; typically 3-5 passes are sufficient to produce a sample with uniform liposome size. The Genizer Multi Online Liposome Extruders System is designed to generate homogeneous unilamellar liposomes and lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The Multi Online Extruders System offers minimal dead volume, is easy to clean, suitable for sterilization and compliant with FDA and GMP sanitary standards in pharmaceuticals.

The Genizer Jacketed Liposome Extruders is compressed air-driven and temperature-controlled, from testing to manufacturing production of liposome and lipopolyplex, for drug and gene delivery. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The process is relatively gentle, exposing the formulation to moderate pressures up to 500 psi at controlled temperatures. The Genizer Jacketed Extruder offers virtually no dead-volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.